ESA’s Technology Transfer Programme Office’s Business Incubation Centres (BICs) support the spin off of space technology to non-space applications and foster new European business based on research and development in European space programmes. Seven BICs in the Netherlands, Italy, Germany, the UK and Belgium are operational supporting over 60 start-ups every year, totalling more than 180 to date. To support the start-up companies further following their BIC-incubation period, ESA has initiated as a limited partner the Open Sky Technology Fund, a €100 million venture fund.